Chemometric Approach in Studying of the Retention Behavior and Lipophilicity of Potentially Biologically ActiveN-Substituted-2-phenylacetamide Derivatives
نویسندگان
چکیده
منابع مشابه
Prediction of Lipophilicity and Pharmacokinetics of Chloroacetamides by Chemometric Approach
In this study, the existence of biological potential of selected N-(substituted phenyl)-2-chloroacetamides was examined none empirically, as was the possibility of applying simpleexperimental technique in predicting essential properties which affect the biological activityof the compounds. By applying the Lipinski and Ghose’s rules, it has been revealed that theexamined chloroacetamides fulfill...
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چکیده ندارد.
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15 صفحه اولPrediction of Lipophilicity and Pharmacokinetics of Chloroacetamides by Chemometric Approach
In this study, the existence of biological potential of selected N-(substituted phenyl)-2-chloroacetamides was examined none empirically, as was the possibility of applying simpleexperimental technique in predicting essential properties which affect the biological activityof the compounds. By applying the Lipinski and Ghose’s rules, it has been revealed that theexamined chloroacetamides fulfill...
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ژورنال
عنوان ژورنال: Journal of the Brazilian Chemical Society
سال: 2014
ISSN: 0103-5053
DOI: 10.5935/0103-5053.20140174